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Incyclix Bio Expands Board of Directors with Appointment of Norman E. Sharpless, MD
Research Triangle Park, N.C. – November 12, 2024 – Incyclix Bio, LLC, a next-generation cell cycle control company developing INX-315, a novel, potent and selective CDK2 inhibitor for the treatment of advanced and resistant cancer, today announced the appointment of Norman E. “Ned” Sharpless, MD, to the Company’s Board of Directors as an independent director. Dr. Sharpless is a physician, scientist and entrepreneur who has led tremendous progress in cancer research and care serving in several leadership roles, including Director of the National Cancer Institute (NCI) and Acting Commissioner of the US Food and Drug Administration (FDA).
“We’re thrilled to welcome Ned, a distinguished oncologist, accomplished scientist and seasoned public servant, to our Board of Directors,” said Patrick Roberts, Pharm.D., Ph.D., Chief Executive Officer and Co-Founder of Incyclix Bio. “Ned brings unparalleled oncology expertise and experience to our Board at this important point in our growth. Ned’s passion and commitment to innovating cancer care and scientific prowess, particularly in cell cycle biology, will be invaluable as we race to bring INX-315 to patients.”
“I have dedicated my career to improving the lives of people affected by cancer,” said Dr. Sharpless. “Incyclix has made exciting progress investigating the potential of its CDK2 inhibitor, INX-315, to provide treatment for patients with advanced and resistant cancer. I look forward to working with Incyclix’s experienced board and leadership team to bring this important novel treatment option to patients in need.”
Dr. Sharpless is a physician, scientist, entrepreneur and former federal official, serving as Director of the National Cancer Institute from 2017 to 2022, and as Acting Commissioner of the FDA in 2019. As a federal official, he led multiple research initiatives spanning cellular immunotherapy, early cancer detection, global oncology and the use of artificial intelligence and machine learning to improve outcomes for patients affected by cancer. Prior to government, Dr. Sharpless was the Wellcome Distinguished Professor of Medicine and Director of the Lineberger Comprehensive Cancer Center at the University of North Carolina (UNC) School of Medicine. He is on the boards Karius Inc., Nucleus Radiopharma, the Eshelman Institute for Innovation, the CEO Roundtable on Cancer and the American Cancer Society; and is the co-Founder and Managing Director of Jupiter BioVentures. He was founder and board member of G1 Therapeutics, which developed the FDA-approved medicine Cosela (Trilaciclib), used to prevent chemotherapy toxicity. He is the Professor of Cancer Policy and Innovation at the UNC School of Medicine, and is a member of the American Association for Cancer Research Academy, the Association of American Physicians, the American Society for Clinical Investigation and the National Academy of Medicine. He received an MD from the UNC School of Medicine, followed by an internal medicine residency at the Massachusetts General Hospital and a hematology/oncology fellowship at the Dana-Farber/Partners Cancer Care, both of Harvard Medical School.
About Incyclix Bio
Incyclix Bio is a next-generation cell cycle control company advancing precision treatments that target the aberrant proliferation driving many cancers. The company’s lead compound, INX-315, is a potent and selective cyclin-dependent kinase 2 (CDK2) inhibitor in clinical development. Incyclix Bio is a scientific leader in understanding cyclin-dependent kinases (CDKs) and their role in the cell cycle as attractive therapeutic targets across many tumor types, including ovarian, breast and lung cancers. Headquartered in Research Triangle Park, NC, Incyclix Bio is founded by pioneers in CDK inhibitor discovery, research and development. For more information, visit incyclixbio.com.
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