INX-315, a Selective CDK2 Inhibitor, Induces Cell Cycle Arrest and Senescence in Solid Tumors

Catherine Dietrich1,2, Alec Trub3, Antonio Ahn1,2, Michael Taylor1,2, Krutika Ambani1,2, Keefe T. Chan1,2,
Kun-Hui Lu1,2, Christabella A. Mahendra1,2, Catherine Blyth1,2, Rhiannon Coulson1,2, Susanne Ramm1,2,
April C. Watt1,2, Sunil Kumar Matsa4, John Bisi3, Jay Strum3, Patrick Roberts3, and Shom Goel1,2

Cancer Discov 2024;14:446–67